Barlow's Syndrome
Barlow's syndrome is a relatively common condition in which there is an abnormality of the mitral valve of the heart. This can sometimes lead to severe mitral regurgitation, in which blood leaks into the left atrium as a result of the incompetent valve during ventricular contraction. Barlow's syndrome is more common in people who suffer from diseases such as Graves' disease, Marfan's syndrome and rheumatic heart disease.
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What Are the Signs and Symptoms of Mitral Valve Prolapse?
Most people who have mitral valve prolapse (MVP) aren't affected by the condition. This is because they don't have any symptoms or major mitral valve backflow.
Among those who do have symptoms, palpitations (strong or rapid heartbeats) are reported most often. Other symptoms include shortness of breath, cough, dizziness, fatigue (tiredness), anxiety, migraine headaches, and chest discomfort.
MVP symptoms can vary from one person to another. They tend to be mild but can worsen over time, mainly when complications occur.
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Mitral Valve Prolapse Complications
Complications of MVP are rare. When present, they're most often due to the backflow of blood through the mitral valve.
Mitral valve backflow is most common among men and people who have high blood pressure. People who have severe cases of backflow may need valve surgery to prevent complications.
Mitral valve backflow causes blood to flow backward from the left ventricle into the left atrium. Blood can even back up from the atrium into the lungs, causing shortness of breath.
The backflow of blood puts a strain on the muscles of both the atrium and the ventricle. Over time, the strain can lead to arrhythmias. Backflow also increases the risk of infective endocarditis (IE), an infection of the inner lining of your heart chambers and valves.
Arrhythmias
Mitral valve backflow can cause arrhythmias. Arrhythmias are problems with the rate or rhythm of the heartbeat.
There are many types of arrhythmia. The most common arrhythmias are harmless. Others can be serious or even life threatening.
When the heart rate is too slow, too fast, or irregular, the heart may not be able to pump enough blood to the body. Lack of blood flow can damage the brain, heart, and other organs.
One troublesome arrhythmia that MVP can cause is atrial fibrillation (AF). In AF, the walls of the atria quiver instead of beating normally. As a result, the atria aren’t able to pump blood into the ventricles the way they should.
AF is bothersome but rarely life threatening, unless the atria contract very fast or blood clots form in the atria. Blood clots can occur because some of the blood "pools" in the atria instead of flowing into the ventricles. If a blood clot breaks off and goes into the bloodstream, it can reach the brain and cause a stroke.
Infection of the Mitral Valve
A deformed mitral valve flap attracts bacteria that may be in the bloodstream. The bacteria attach to the valve and can cause a serious infection called infective endocarditis (IE). Signs and symptoms of a bacterial infection include fever, chills, body aches, or headaches.
IE doesn't happen often, but when it does, it's serious. MVP is the most common heart condition that puts people at risk for this infection.
You can take steps to prevent this infection. Floss and brush your teeth regularly. Gum infections and tooth decay can cause IE.